WebNov 23, 2024 · This represents a striking ability to separate the function of TAX1BP1 in these processes, dependent solely on TAX1BP1's ability to bind TBK1 and/or FIP200. The … Web#bioart分享# ——【Mol Cell丨TNIP1:线粒体自噬的“安全检查员”】 2024年3月9日,来自美国国立卫生研究院的Richard J. Youle团队在#Molecular Cell#在线发表题为 #TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1# 的文章,发现TNIP1通过与TAX1BP1和FIP200以竞争性方式结合而发挥了线粒体自噬 ...
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WebMar 9, 2024 · Le Guerroué et al. show that TNIP1 acts as an inhibitor of mitophagy by binding with TAX1BP1 and FIP200 in a competitive manner. While binding to TAX1BP1 is … Web微信公众号BioArt介绍:高屋建瓴,提供专家点评,引导学术争论,展现学术批评;诚心实意,关注科研生态,推广科研经验,倡导师生交流。;Mol Cell丨TNIP1:线粒体自噬的“安 … jens ramge axa
Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 …
Web2024年3月9日,来自美国国立卫生研究院的 Richard J. Youle 团队在 Molecular Cell 在线发表题为 TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1 的文章, 发现TNIP1通过与TAX1BP1和FIP200以竞争性方式结合而发挥了线粒体自噬抑制因子的作用,不仅证实与TAX1BP1结合对TNIP1的抑制作用至关重要 ... WebOct 23, 2007 · Functions as a DNA-binding transcription factor ( PubMed: 12095676 ). Is a potent regulator of the RB1 pathway through induction of RB1 expression ( PubMed: … WebNov 23, 2024 · and TBK1. TAX1BP1’s ability to cluster FIP200 around NBR1 cargo and induce local autophagosome formation enforces cargo speci-ficity and replaces the … jens rannow ulm