Witryna30 cze 2024 · Here, we identified a class of small cytosolic DNAs (scDNAs) of ∼20–40 bp in human and mouse cell lines. scDNAs competed with herring testis DNA (HT-DNA, ∼200–1500 bp) for binding to cGAS, and repressing HT-DNA-induced cGAS activation and the associated interferon β (IFNβ) production. Witryna脱氧核糖核酸来源于鲱鱼精子,鲱鱼精DNA (hsDNA)是一种天然的DNA用于研究DNA绑定抗癌剂和DNA绑定代理,调节DNA结构和功能。 溶解性:水溶,5mg/ml,不能完全溶 …
Herring Testis Dna Millipore Bioz
Witrynaherring testis DNA (HT-DNA; fig. S1C) activated IRF3 in permeabilized THP1 cells, indicating that this activity was independent of DNA sequence. To determine if the STING activa- WitrynaNational Center for Biotechnology Information chaise sofa and loveseat set
Ku proteins promote DNA binding and condensation of cyclic …
Witryna7 mar 2024 · As expected, these cells failed to induce IRF3 phosphorylation and IFN production upon stimulation by introducing herring testis DNA (HT-DNA) into the cells. This deficiency could be rescued by wild-type cGAS but not acetylation-mimicking cGAS (Figures 1 C and 1D). Witrynaデオキシリボ核酸 ナトリウム塩 from herring testes Type XIV; CAS Number: 438545-06-3; Synonyms: DNA; find Sigma-Aldrich-D6898 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich ... Deoxyribonucleic acid sodium salt from herring testes, also known as HtDNA is a natural source of DNA ... Witryna15 maj 2024 · In addition to inhibiting transcription in the MLFs, PCBP1 deficiency inhibited HSV-1- and herring testis DNA (HT-DNA)-induced transcription of the IFNB1, ISG56, and IL6 genes in the human ... chaise sofa living spaces