Cisplatin medication interactions
Web2 days ago · One of the main problems in chemotherapy using platinum drugs as anticancer agents is the resistance phenomenon. Synthesizing and evaluating valid alternative compounds is challenging. This review focuses on the last two years of progress in the studies of platinum (II)- and platinum (IV)-based anticancer complexes. In particular, the … WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel …
Cisplatin medication interactions
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WebIn metal ion introduction SLNs, the compact degree of the lipid molecules was increased due to the electrostatic interaction between metal ions and phospholipid acyl and choline polarity groups, which result in increasing of drug EE. Meanwhile, these electrostatic interactions slowed the releasing rate of encapsulated drug. WebCisplatin Disease Interactions There are 7 disease interactions with cisplatin. Infections Hearing loss Myelosuppression Peripheral neuropathy Renal dysfunction Hemolytic …
WebSep 18, 2024 · Caution is necessary when administering cisplatin with any of the following medications. Most drug interactions result in cumulative and dose-dependent hematologic, renal, and neurotoxic effects. Due to cumulative myelosuppression, cisplatin should also not be used concurrently with immunosuppressive medications. [28] [29] … WebDrug Interactions between cisplatin and Vitamin B12. This report displays the potential drug interactions for the following 2 drugs: cisplatin. Vitamin B12(cyanocobalamin) …
WebSep 15, 2024 · Cisplatin may interact with anticonvulsants, or pyridoxine ( Vitamin B6 ). Tell your doctor all medications and supplements you use. What Drugs, Substances, or Supplements Interact with Cisplatin? Cisplatin is not recommended for use during pregnancy; it may harm a fetus. Cisplatin During Pregnancy and Breastfeeding WebJan 20, 2011 · Pharmaceutical Interactions Pharmaceutical interactions occur because of a physical or chemical incompatibility. A classic example of an unwanted pharmaceutical interaction is the inactivation of the platinum compound cisplatin by the addition of the thiol mesna (sodium 2-mercaptoethanesulfonate).
WebFeb 1, 2024 · Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems The presence of other medical problems may affect the use of this medicine.
WebApr 14, 2024 · Huixin Tan. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of … cineworld shaw ridge screen 6WebCisplatin has a possibility to interact with more drugs. These interactions are harmful. Drug interactions can be prevented by avoiding unwanted drug combinations. diagnosing knee injury by pain locationWebMay 11, 2012 · Cisplatin can increase your chance of unusual bleeding or bruising because it can lower the number of platelets in your blood. Cisplatin Food Interactions Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. diagnosing lawn mower starter turns slowlyWebSep 15, 2024 · The most common side effects of Cisplatin include: nausea, vomiting (may be severe), diarrhea, temporary hair loss, loss in ability to taste food, hiccups, dry mouth, … diagnosing knee pain chartWebSep 24, 2024 · Cisplatin exerts anticancer activity via multiple mechanisms. Its most acceptable mechanism involves the formation of DNA–platinum adducts by interacting with purine bases, activating several signal transduction pathways, and silencing or activating several genes which finally leads to apoptosis. diagnosing kids with adhdWebApr 14, 2024 · Since HK-2-cells-generated-Abs, both by cisplatin or upon UV light exposure, can induce apoptosis in HK-2 cells, the purpose of this work was to study their metabolome and therein find the molecular features which help us to unravel the mechanisms of that phenomenon. diagnosing learning difficultiesWebSep 1, 2024 · Cisplatin for injection can cause severe hypersensitivity reactions, including anaphylaxis and death. Manifestations have included facial edema, wheezing, … diagnosing kohler shower mixer problem